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Drug Description of Subutex Pill (Buprenorphine)
SUBUTEX (Buprenorphine) sublingual tablet is an uncoated oval white flat bevelled edged tablet, debossed with an alphanumeric word identifying the product and strength on one side. It contains buprenorphine HCl, a partial agonist at the mu-opioid receptor, and is available in two dosage strengths, 2 mg buprenorphine and 8 mg buprenorphine. It can be used under the tongue, in the cheek, by injection, as a skin patch, or as an implant. For opioid use disorder, it is typically started when withdrawal symptoms have begun.
Uses of Subutex
SUBUTEX is indicated for the treatment of opioid dependence and is preferred for induction. It is also used for the treatment of acute and chronic pain.
Dosage and Administration
Prior to induction, consideration should be given to the type of opioid dependence (i.e., long-or short-acting opioid products), the time since last opioid use, and the degree or level of opioid dependence. Dosage should be individualized for maximum beneficial effect.
Dosage should be individualized for maximum beneficial effect.
Side Effects of Use
Side effects may include respiratory depression (decreased breathing), sleepiness, adrenal insufficiency, low blood pressure, allergic reactions, constipation, and opioid addiction. Among those with a history of seizures, there is a risk of further seizures. Opioid withdrawal following stopping buprenorphine is generally less severe than with other opioids. It is unclear if use during pregnancy is safe and use while breastfeeding is not recommended.